diff --git a/em-config b/em-config
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/em-config
+++ b/em-config
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/em-config.bat b/em-config.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/em-config.bat
+++ b/em-config.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emar b/emar
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/emar
+++ b/emar
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emar.bat b/emar.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/emar.bat
+++ b/emar.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/embuilder b/embuilder
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/embuilder
+++ b/embuilder
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/embuilder.bat b/embuilder.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/embuilder.bat
+++ b/embuilder.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emcmake b/emcmake
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/emcmake
+++ b/emcmake
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emcmake.bat b/emcmake.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/emcmake.bat
+++ b/emcmake.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emconfigure b/emconfigure
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/emconfigure
+++ b/emconfigure
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emconfigure.bat b/emconfigure.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/emconfigure.bat
+++ b/emconfigure.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emdump b/emdump
index b60c6e0083469..2e57aac08add3 100755
--- a/emdump
+++ b/emdump
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emdump.bat b/emdump.bat
index c0d7d3ecd28e8..9c6bfe5e7730d 100644
--- a/emdump.bat
+++ b/emdump.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emdwp b/emdwp
index f39d54e64288c..738c0f9f3edcc 100755
--- a/emdwp
+++ b/emdwp
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emdwp.bat b/emdwp.bat
index 3c056794f3564..8bf4188c60d06 100644
--- a/emdwp.bat
+++ b/emdwp.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emmake b/emmake
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/emmake
+++ b/emmake
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emmake.bat b/emmake.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/emmake.bat
+++ b/emmake.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emnm b/emnm
index 4920cf7017247..063ca060c3a68 100755
--- a/emnm
+++ b/emnm
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emnm.bat b/emnm.bat
index 4257155a7a8d9..82d579f55b4bd 100644
--- a/emnm.bat
+++ b/emnm.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emprofile b/emprofile
index 998a39e28d0cf..010014eea221e 100755
--- a/emprofile
+++ b/emprofile
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emprofile.bat b/emprofile.bat
index 5908117caad95..b2f580f560bba 100644
--- a/emprofile.bat
+++ b/emprofile.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emranlib b/emranlib
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/emranlib
+++ b/emranlib
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emranlib.bat b/emranlib.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/emranlib.bat
+++ b/emranlib.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emrun b/emrun
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/emrun
+++ b/emrun
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emrun.bat b/emrun.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/emrun.bat
+++ b/emrun.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emscons b/emscons
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/emscons
+++ b/emscons
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emscons.bat b/emscons.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/emscons.bat
+++ b/emscons.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emsize b/emsize
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/emsize
+++ b/emsize
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emsize.bat b/emsize.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/emsize.bat
+++ b/emsize.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emstrip b/emstrip
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/emstrip
+++ b/emstrip
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emstrip.bat b/emstrip.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/emstrip.bat
+++ b/emstrip.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/emsymbolizer b/emsymbolizer
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/emsymbolizer
+++ b/emsymbolizer
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/emsymbolizer.bat b/emsymbolizer.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/emsymbolizer.bat
+++ b/emsymbolizer.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/system/bin/sdl-config b/system/bin/sdl-config
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/system/bin/sdl-config
+++ b/system/bin/sdl-config
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/system/bin/sdl-config.bat b/system/bin/sdl-config.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/system/bin/sdl-config.bat
+++ b/system/bin/sdl-config.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/system/bin/sdl2-config b/system/bin/sdl2-config
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/system/bin/sdl2-config
+++ b/system/bin/sdl2-config
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/system/bin/sdl2-config.bat b/system/bin/sdl2-config.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/system/bin/sdl2-config.bat
+++ b/system/bin/sdl2-config.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/test/runner b/test/runner
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/test/runner
+++ b/test/runner
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/test/runner.bat b/test/runner.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/test/runner.bat
+++ b/test/runner.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/tools/file_packager b/tools/file_packager
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/tools/file_packager
+++ b/tools/file_packager
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/tools/file_packager.bat b/tools/file_packager.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/tools/file_packager.bat
+++ b/tools/file_packager.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/tools/run_python.bat b/tools/run_python.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/tools/run_python.bat
+++ b/tools/run_python.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python
diff --git a/tools/run_python.sh b/tools/run_python.sh
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/tools/run_python.sh
+++ b/tools/run_python.sh
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/tools/webidl_binder b/tools/webidl_binder
index 1a3a1c9691685..34eaae2cc79b4 100755
--- a/tools/webidl_binder
+++ b/tools/webidl_binder
@@ -11,10 +11,6 @@
 # To make modifications to this file, edit `tools/run_python.sh` and then run
 # `tools/create_entry_points.py`
 
-# $PYTHON -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-# of cpython used in cross compilation via setup.py.
-unset _PYTHON_SYSCONFIGDATA_NAME
-
 if [ -z "$PYTHON" ]; then
   PYTHON=$EMSDK_PYTHON
 fi
diff --git a/tools/webidl_binder.bat b/tools/webidl_binder.bat
index 34900168d5856..deb8d5e6e8014 100644
--- a/tools/webidl_binder.bat
+++ b/tools/webidl_binder.bat
@@ -10,9 +10,6 @@
 
 :: All env. vars specified in this file are to be local only to this script.
 @setlocal
-:: -E will not ignore _PYTHON_SYSCONFIGDATA_NAME an internal
-:: of cpython used in cross compilation via setup.py.
-@set _PYTHON_SYSCONFIGDATA_NAME=
 @set EM_PY=%EMSDK_PYTHON%
 @if "%EM_PY%"=="" (
   set EM_PY=python