diff --git a/llvm/lib/Transforms/Utils/ModuleUtils.cpp b/llvm/lib/Transforms/Utils/ModuleUtils.cpp
index 7249571f34493..208d49da04a37 100644
--- a/llvm/lib/Transforms/Utils/ModuleUtils.cpp
+++ b/llvm/lib/Transforms/Utils/ModuleUtils.cpp
@@ -433,6 +433,10 @@ bool llvm::lowerGlobalIFuncUsersAsGlobalCtor(
       FunctionType::get(Type::getVoidTy(Ctx), false), Function::InternalLinkage,
       DL.getProgramAddressSpace(), "", &M);
 
+  // Disable Sanitizers as they might not yet initialized when the contructor
+  // runs.
+  NewCtor->addFnAttr(llvm::Attribute::DisableSanitizerInstrumentation);
+
   BasicBlock *BB = BasicBlock::Create(Ctx, "", NewCtor);
   IRBuilder<> InitBuilder(BB);
 
diff --git a/llvm/test/tools/llvm-reduce/ifunc-alias.ll b/llvm/test/tools/llvm-reduce/ifunc-alias.ll
index 258eb00383f7e..01337a7abc0f1 100644
--- a/llvm/test/tools/llvm-reduce/ifunc-alias.ll
+++ b/llvm/test/tools/llvm-reduce/ifunc-alias.ll
@@ -60,9 +60,10 @@ define float @call_alias_of_ifunc(i64 %arg) {
   ret float %call
 }
 
-; CHECK-FINAL-BOTH: define internal void [[CONSTRUCTOR]]() {
+; CHECK-FINAL-BOTH: define internal void [[CONSTRUCTOR]]() #[[#CONSTRUCTOR_ATTR:]] {
 ; CHECK-FINAL-BOTH-NEXT: %1 = call ptr @resolver()
 ; CHECK-FINAL-BOTH-NEXT: store ptr %1, ptr [[TABLE]], align 8
 ; CHECK-FINAL-BOTH-NEXT: %2 = call ptr @resolver()
 ; CHECK-FINAL-BOTH-NEXT: store ptr %2, ptr getelementptr inbounds ([2 x ptr], ptr [[TABLE]], i32 0, i32 1), align 8
 ; CHECK-FINAL-BOTH-NEXT: ret void
+; CHECK-FINAL-DAG: attributes #[[#CONSTRUCTOR_ATTR]] = {{{.*}} disable_sanitizer_instrumentation {{.*}}
diff --git a/llvm/test/tools/llvm-reduce/remove-ifunc-program-addrspace.ll b/llvm/test/tools/llvm-reduce/remove-ifunc-program-addrspace.ll
index e275d61764b21..450448d11c6a6 100644
--- a/llvm/test/tools/llvm-reduce/remove-ifunc-program-addrspace.ll
+++ b/llvm/test/tools/llvm-reduce/remove-ifunc-program-addrspace.ll
@@ -90,7 +90,7 @@ define void @load_removed() addrspace(0) {
   ret void
 }
 
-; CHECK-FINAL: define internal void [[TABLE_CTOR]]() addrspace(1) {
+; CHECK-FINAL: define internal void [[TABLE_CTOR]]() addrspace(1) #[[#CONSTRUCTOR_ATTR:]] {
 ; CHECK-FINAL-NEXT: %1 = call addrspace(1) ptr addrspace(1) @resolver1_in_1()
 ; CHECK-FINAL-NEXT: store ptr addrspace(1) %1, ptr addrspace(2) [[TABLE]], align 8
 ; CHECK-FINAL-NEXT: %2 = call addrspace(0) ptr addrspace(1) @resolver1_in_0()
@@ -105,3 +105,4 @@ define void @load_removed() addrspace(0) {
 ; CHECK-FINAL-NEXT: %7 = call addrspace(0) ptr addrspace(1) @resolver1_in_0()
 ; CHECK-FINAL-NEXT: store ptr addrspace(1) %7, ptr addrspace(2) getelementptr inbounds ([6 x ptr addrspace(1)], ptr addrspace(2) [[TABLE]], i32 0, i32 5), align 8
 ; CHECK-FINAL-NEXT: ret void
+; CHECK-FINAL-DAG: attributes #[[#CONSTRUCTOR_ATTR]] = {{{.*}} disable_sanitizer_instrumentation {{.*}}
diff --git a/llvm/test/tools/llvm-reduce/remove-ifunc.ll b/llvm/test/tools/llvm-reduce/remove-ifunc.ll
index a7853d937d9a6..33cadd134245a 100644
--- a/llvm/test/tools/llvm-reduce/remove-ifunc.ll
+++ b/llvm/test/tools/llvm-reduce/remove-ifunc.ll
@@ -177,7 +177,7 @@ define i32 @call_used_in_initializer(double %arg) {
   ret i32 %ret
 }
 
-; CHECK-FINAL-LABEL: define internal void @1() {
+; CHECK-FINAL-LABEL: define internal void @1() #[[#CONSTRUCTOR_ATTR:]] {
 ; CHECK-FINAL-NEXT: %1 = call ptr @resolver1()
 ; CHECK-FINAL-NEXT: store ptr %1, ptr @0, align 8
 ; CHECK-FINAL-NEXT: %2 = call ptr @resolver2()
@@ -196,3 +196,4 @@ define i32 @call_used_in_initializer(double %arg) {
 ; CHECK-FINAL-NEXT: store ptr %8, ptr getelementptr inbounds ([8 x ptr], ptr @0, i32 0, i32 7), align 8
 ; CHECK-FINAL-NEXT: ret void
 ; CHECK-FINAL-NEXT: }
+; CHECK-FINAL-DAG: attributes #[[#CONSTRUCTOR_ATTR]] = {{{.*}} disable_sanitizer_instrumentation {{.*}}