diff --git a/compiler-rt/test/asan/lit.cfg.py b/compiler-rt/test/asan/lit.cfg.py
index 2da511103da7c..3da073332c458 100644
--- a/compiler-rt/test/asan/lit.cfg.py
+++ b/compiler-rt/test/asan/lit.cfg.py
@@ -25,8 +25,13 @@ def get_required_attr(config, attr_name):
 default_asan_opts = list(config.default_sanitizer_opts)
 
 # On Darwin, leak checking is not enabled by default. Enable on macOS
-# tests to prevent regressions
-if config.host_os == "Darwin" and config.apple_platform == "osx":
+# tests to prevent regressions.
+# Currently, detect_leaks for asan tests only work on Intel MacOS.
+if (
+    config.host_os == "Darwin"
+    and config.apple_platform == "osx"
+    and config.target_arch == "x86_64"
+):
     default_asan_opts += ["detect_leaks=1"]
 
 default_asan_opts_str = ":".join(default_asan_opts)
@@ -273,7 +278,11 @@ def build_invocation(compile_flags, with_lto=False):
     and (not config.android)
     and (config.target_arch in ["x86_64", "i386", "riscv64", "loongarch64"])
 )
-leak_detection_mac = (config.host_os == "Darwin") and (config.apple_platform == "osx")
+leak_detection_mac = (
+    (config.host_os == "Darwin")
+    and (config.apple_platform == "osx")
+    and (config.target_arch == "x86_64")
+)
 leak_detection_netbsd = (config.host_os == "NetBSD") and (
     config.target_arch in ["x86_64", "i386"]
 )