diff --git a/src/compiler/checker.ts b/src/compiler/checker.ts
index caab75c99fa8a..c3542de04d819 100644
--- a/src/compiler/checker.ts
+++ b/src/compiler/checker.ts
@@ -27097,8 +27097,18 @@ export function createTypeChecker(host: TypeCheckerHost): TypeChecker {
             case SyntaxKind.NonNullExpression:
                 return isMatchingReference(source, (target as NonNullExpression | ParenthesizedExpression).expression);
             case SyntaxKind.BinaryExpression:
-                return (isAssignmentExpression(target) && isMatchingReference(source, target.left)) ||
-                    (isBinaryExpression(target) && target.operatorToken.kind === SyntaxKind.CommaToken && isMatchingReference(source, target.right));
+                if (isAssignmentExpression(target)) {
+                    return isMatchingReference(source, target.left);
+                }
+                if (isBinaryExpression(target)) {
+                    switch (target.operatorToken.kind) {
+                        case SyntaxKind.CommaToken:
+                            return isMatchingReference(source, target.right);
+                        case SyntaxKind.InKeyword:
+                            return isMatchingElementAccess(source, target.right, target.left);
+                    }
+                }
+                return false;
         }
         switch (source.kind) {
             case SyntaxKind.MetaProperty:
@@ -27129,12 +27139,7 @@ export function createTypeChecker(host: TypeCheckerHost): TypeChecker {
                         return targetPropertyName === sourcePropertyName && isMatchingReference((source as AccessExpression).expression, (target as AccessExpression).expression);
                     }
                 }
-                if (isElementAccessExpression(source) && isElementAccessExpression(target) && isIdentifier(source.argumentExpression) && isIdentifier(target.argumentExpression)) {
-                    const symbol = getResolvedSymbol(source.argumentExpression);
-                    if (symbol === getResolvedSymbol(target.argumentExpression) && (isConstantVariable(symbol) || isParameterOrMutableLocalVariable(symbol) && !isSymbolAssigned(symbol))) {
-                        return isMatchingReference(source.expression, target.expression);
-                    }
-                }
+                return isElementAccessExpression(target) && isMatchingElementAccess(source, target.expression, target.argumentExpression);
                 break;
             case SyntaxKind.QualifiedName:
                 return isAccessExpression(target) &&
@@ -27144,6 +27149,15 @@ export function createTypeChecker(host: TypeCheckerHost): TypeChecker {
                 return (isBinaryExpression(source) && source.operatorToken.kind === SyntaxKind.CommaToken && isMatchingReference(source.right, target));
         }
         return false;
+
+        function isMatchingElementAccess(source: Node, targetObjNode: Node, targetPropNode: Node): boolean {
+            if (!isElementAccessExpression(source) || !isIdentifier(source.argumentExpression) || !isIdentifier(targetPropNode)) {
+                return false;
+            }
+            const symbol = getResolvedSymbol(source.argumentExpression);
+            return (symbol === getResolvedSymbol(targetPropNode) && (isConstantVariable(symbol) || isParameterOrMutableLocalVariable(symbol) && !isSymbolAssigned(symbol)))
+                && isMatchingReference(source.expression, targetObjNode);
+        }
     }
 
     function getAccessedPropertyName(access: AccessExpression | BindingElement | ParameterDeclaration): __String | undefined {
@@ -28943,7 +28957,11 @@ export function createTypeChecker(host: TypeCheckerHost): TypeChecker {
                     const target = getReferenceCandidate(expr.right);
                     if (containsMissingType(type) && isAccessExpression(reference) && isMatchingReference(reference.expression, target)) {
                         const leftType = getTypeOfExpression(expr.left);
-                        if (isTypeUsableAsPropertyName(leftType) && getAccessedPropertyName(reference) === getPropertyNameFromType(leftType)) {
+                        if (
+                            isTypeUsableAsPropertyName(leftType)
+                                ? getAccessedPropertyName(reference) === getPropertyNameFromType(leftType)
+                                : isMatchingReference(reference, expr)
+                        ) {
                             return getTypeWithFacts(type, assumeTrue ? TypeFacts.NEUndefined : TypeFacts.EQUndefined);
                         }
                     }
diff --git a/tests/baselines/reference/controlFlowComputedPropertyNames2.symbols b/tests/baselines/reference/controlFlowComputedPropertyNames2.symbols
new file mode 100644
index 0000000000000..32bb4e796c6b4
--- /dev/null
+++ b/tests/baselines/reference/controlFlowComputedPropertyNames2.symbols
@@ -0,0 +1,39 @@
+//// [tests/cases/conformance/controlFlow/controlFlowComputedPropertyNames2.ts] ////
+
+=== controlFlowComputedPropertyNames2.ts ===
+// https://github.com/microsoft/TypeScript/issues/61389
+
+const arr: number[] = [1, 2, 3];
+>arr : Symbol(arr, Decl(controlFlowComputedPropertyNames2.ts, 2, 5))
+
+const idx: number = 2;
+>idx : Symbol(idx, Decl(controlFlowComputedPropertyNames2.ts, 3, 5))
+
+if (idx in arr) {
+>idx : Symbol(idx, Decl(controlFlowComputedPropertyNames2.ts, 3, 5))
+>arr : Symbol(arr, Decl(controlFlowComputedPropertyNames2.ts, 2, 5))
+
+  const x: number = arr[idx]; // ok
+>x : Symbol(x, Decl(controlFlowComputedPropertyNames2.ts, 5, 7))
+>arr : Symbol(arr, Decl(controlFlowComputedPropertyNames2.ts, 2, 5))
+>idx : Symbol(idx, Decl(controlFlowComputedPropertyNames2.ts, 3, 5))
+}
+
+const map: Record<string, number> = { a: 1 };
+>map : Symbol(map, Decl(controlFlowComputedPropertyNames2.ts, 8, 5))
+>Record : Symbol(Record, Decl(lib.es5.d.ts, --, --))
+>a : Symbol(a, Decl(controlFlowComputedPropertyNames2.ts, 8, 37))
+
+const key: string = "a";
+>key : Symbol(key, Decl(controlFlowComputedPropertyNames2.ts, 9, 5))
+
+if (key in map) {
+>key : Symbol(key, Decl(controlFlowComputedPropertyNames2.ts, 9, 5))
+>map : Symbol(map, Decl(controlFlowComputedPropertyNames2.ts, 8, 5))
+
+  const x: number = map[key]; // ok
+>x : Symbol(x, Decl(controlFlowComputedPropertyNames2.ts, 11, 7))
+>map : Symbol(map, Decl(controlFlowComputedPropertyNames2.ts, 8, 5))
+>key : Symbol(key, Decl(controlFlowComputedPropertyNames2.ts, 9, 5))
+}
+
diff --git a/tests/baselines/reference/controlFlowComputedPropertyNames2.types b/tests/baselines/reference/controlFlowComputedPropertyNames2.types
new file mode 100644
index 0000000000000..fd358950403d8
--- /dev/null
+++ b/tests/baselines/reference/controlFlowComputedPropertyNames2.types
@@ -0,0 +1,77 @@
+//// [tests/cases/conformance/controlFlow/controlFlowComputedPropertyNames2.ts] ////
+
+=== controlFlowComputedPropertyNames2.ts ===
+// https://github.com/microsoft/TypeScript/issues/61389
+
+const arr: number[] = [1, 2, 3];
+>arr : number[]
+>    : ^^^^^^^^
+>[1, 2, 3] : number[]
+>          : ^^^^^^^^
+>1 : 1
+>  : ^
+>2 : 2
+>  : ^
+>3 : 3
+>  : ^
+
+const idx: number = 2;
+>idx : number
+>    : ^^^^^^
+>2 : 2
+>  : ^
+
+if (idx in arr) {
+>idx in arr : boolean
+>           : ^^^^^^^
+>idx : number
+>    : ^^^^^^
+>arr : number[]
+>    : ^^^^^^^^
+
+  const x: number = arr[idx]; // ok
+>x : number
+>  : ^^^^^^
+>arr[idx] : number
+>         : ^^^^^^
+>arr : number[]
+>    : ^^^^^^^^
+>idx : number
+>    : ^^^^^^
+}
+
+const map: Record<string, number> = { a: 1 };
+>map : Record<string, number>
+>    : ^^^^^^^^^^^^^^^^^^^^^^
+>{ a: 1 } : { a: number; }
+>         : ^^^^^^^^^^^^^^
+>a : number
+>  : ^^^^^^
+>1 : 1
+>  : ^
+
+const key: string = "a";
+>key : string
+>    : ^^^^^^
+>"a" : "a"
+>    : ^^^
+
+if (key in map) {
+>key in map : boolean
+>           : ^^^^^^^
+>key : string
+>    : ^^^^^^
+>map : Record<string, number>
+>    : ^^^^^^^^^^^^^^^^^^^^^^
+
+  const x: number = map[key]; // ok
+>x : number
+>  : ^^^^^^
+>map[key] : number
+>         : ^^^^^^
+>map : Record<string, number>
+>    : ^^^^^^^^^^^^^^^^^^^^^^
+>key : string
+>    : ^^^^^^
+}
+
diff --git a/tests/cases/conformance/controlFlow/controlFlowComputedPropertyNames2.ts b/tests/cases/conformance/controlFlow/controlFlowComputedPropertyNames2.ts
new file mode 100644
index 0000000000000..7e25b3bba6d3e
--- /dev/null
+++ b/tests/cases/conformance/controlFlow/controlFlowComputedPropertyNames2.ts
@@ -0,0 +1,17 @@
+// @strict: true
+// @noUncheckedIndexedAccess: true
+// @noEmit: true
+
+// https://github.com/microsoft/TypeScript/issues/61389
+
+const arr: number[] = [1, 2, 3];
+const idx: number = 2;
+if (idx in arr) {
+  const x: number = arr[idx]; // ok
+}
+
+const map: Record<string, number> = { a: 1 };
+const key: string = "a";
+if (key in map) {
+  const x: number = map[key]; // ok
+}