diff --git a/compiler/rustc_hir/src/lang_items.rs b/compiler/rustc_hir/src/lang_items.rs
index 6347f1bfa714d..75c04b23ed6e8 100644
--- a/compiler/rustc_hir/src/lang_items.rs
+++ b/compiler/rustc_hir/src/lang_items.rs
@@ -345,9 +345,6 @@ language_item_table! {
     OwnedBox,                sym::owned_box,           owned_box,                  Target::Struct,         GenericRequirement::Minimum(1);
     GlobalAlloc,             sym::global_alloc_ty,     global_alloc_ty,            Target::Struct,         GenericRequirement::None;
 
-    // Experimental lang item for Miri
-    PtrUnique,               sym::ptr_unique,          ptr_unique,                 Target::Struct,         GenericRequirement::Exact(1);
-
     PhantomData,             sym::phantom_data,        phantom_data,               Target::Struct,         GenericRequirement::Exact(1);
 
     ManuallyDrop,            sym::manually_drop,       manually_drop,              Target::Struct,         GenericRequirement::None;
diff --git a/compiler/rustc_mir_transform/src/add_retag.rs b/compiler/rustc_mir_transform/src/add_retag.rs
index 3c29d4624b73c..fc08c1df8703a 100644
--- a/compiler/rustc_mir_transform/src/add_retag.rs
+++ b/compiler/rustc_mir_transform/src/add_retag.rs
@@ -4,7 +4,6 @@
 //! of MIR building, and only after this pass we think of the program has having the
 //! normal MIR semantics.
 
-use rustc_hir::LangItem;
 use rustc_middle::mir::*;
 use rustc_middle::ty::{self, Ty, TyCtxt};
 
@@ -28,7 +27,6 @@ fn may_contain_reference<'tcx>(ty: Ty<'tcx>, depth: u32, tcx: TyCtxt<'tcx>) -> b
         // References and Boxes (`noalias` sources)
         ty::Ref(..) => true,
         ty::Adt(..) if ty.is_box() => true,
-        ty::Adt(adt, _) if tcx.is_lang_item(adt.did(), LangItem::PtrUnique) => true,
         // Compound types: recurse
         ty::Array(ty, _) | ty::Slice(ty) => {
             // This does not branch so we keep the depth the same.
diff --git a/compiler/rustc_span/src/symbol.rs b/compiler/rustc_span/src/symbol.rs
index d28a73bc13978..d0d09862ade29 100644
--- a/compiler/rustc_span/src/symbol.rs
+++ b/compiler/rustc_span/src/symbol.rs
@@ -1698,7 +1698,6 @@ symbols! {
         ptr_slice_from_raw_parts_mut,
         ptr_swap,
         ptr_swap_nonoverlapping,
-        ptr_unique,
         ptr_write,
         ptr_write_bytes,
         ptr_write_unaligned,
diff --git a/library/core/src/ptr/unique.rs b/library/core/src/ptr/unique.rs
index c069314ff7d23..e9e13f9e97f84 100644
--- a/library/core/src/ptr/unique.rs
+++ b/library/core/src/ptr/unique.rs
@@ -32,8 +32,6 @@ use crate::ptr::NonNull;
 )]
 #[doc(hidden)]
 #[repr(transparent)]
-// Lang item used experimentally by Miri to define the semantics of `Unique`.
-#[lang = "ptr_unique"]
 pub struct Unique<T: PointeeSized> {
     pointer: NonNull<T>,
     // NOTE: this marker has no consequences for variance, but is necessary