diff --git a/NEWS.md b/NEWS.md
index 747eebf6bb..5b4d074c57 100644
--- a/NEWS.md
+++ b/NEWS.md
@@ -1,5 +1,8 @@
 # ggplot2 (development version)
 
+* `ScaleContinuous$get_breaks()` now only calls `scales::zero_range()` on limits
+  in transformed space, rather than in data space (#5304).
+
 * Scales throw more informative messages (@teunbrand, #4185, #4258)
 
 * The `scale_name` argument in `continuous_scale()`, `discrete_scale()` and
diff --git a/R/scale-.R b/R/scale-.R
index 9a9ef4f4c9..eb4248048d 100644
--- a/R/scale-.R
+++ b/R/scale-.R
@@ -691,7 +691,9 @@ ScaleContinuous <- ggproto("ScaleContinuous", Scale,
       )
     }
 
-    if (zero_range(as.numeric(limits))) {
+    # Compute `zero_range()` in transformed space in case `limits` in data space
+    # don't support conversion to numeric (#5304)
+    if (zero_range(as.numeric(self$trans$transform(limits)))) {
       breaks <- limits[1]
     } else if (is.waive(self$breaks)) {
       if (!is.null(self$n.breaks) && trans_support_nbreaks(self$trans)) {